http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104147614-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
| filingDate | 2013-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104147614-B |
| titleOfInvention | A kind of polyethyleneglycol modified nano particle of Alendronic acid functionalization and preparation method thereof |
| abstract | The invention provides the polyethyleneglycol modified nano particle of a kind of Alendronic acid functionalization; nano particle is to be enclosed with target to deliver calcium phosphate granules or the calcium carbonate granule of thing; target delivers thing selected from DNA, siRNA, protein-based macromolecular drug or small-molecule chemical medicine; the polyethylene glycol of Alendronic acid functionalization covers at nano grain surface, and the polyethyleneglycol modified nano particle diameter of Alendronic acid functionalization is 20～50nm.The polyethyleneglycol modified nano particle diameter of this Alendronic acid functionalization is little, the covering that many Alendronic acids polyethylene glycol can consolidate at phosphate base because of particle surface, thus effectively and long-time stable nano particle, extend the time of body-internal-circulation, low cost, low toxicity, safely and effectively.Present invention also offers the preparation method of the polyethyleneglycol modified nano particle of this Alendronic acid functionalization. |
| priorityDate | 2013-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 113.