http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104147002-B

Outgoing Links

Predicate Object
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-138
filingDate 2014-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2016-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104147002-B
titleOfInvention Indapamide bisoprolol transdermal skin patches and preparation method thereof
abstract The invention belongs to pharmaceutical technology field, relate to indapamide bisoprolol transdermal skin patches and preparation method thereof.Described indapamide bisoprolol transdermal skin patches is made up of backing layer, medicine carrying pressure-sensitive adhesive layer and adherent layer;Medicine carrying pressure-sensitive adhesive layer includes that indapamide, bisoprolol free alkali or its organic acid ion are to complex, pressure sensitive adhesive, transdermal absorption accelerator.Wherein indapamide, bisoprolol free alkali or its organic acid ion dose total to complex accounts for the 0.5wt% ~ 5.5wt% of medicine carrying pressure-sensitive adhesive layer gross weight, wherein indopamide, bisoprolol free alkali or its organic acid ion are 0.5:1 ~ 2:1 to the molar ratio of complex, the present invention is capable of in transdermal skin patches passing through indapamide and bisoprolol percutaneous the two-ways regulation of ability, it is achieved that two medicines pass through from the synchronized of transdermal skin patches.
priorityDate 2014-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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