abstract |
The invention relates to a dexibuprofen injection and a preparation method thereof, and particularly relates to a dexibuprofen injection prepared by using poloxamer-188 as a cosolvent and a preparation method thereof. In the injection, the weight ratio of dexibuprofen to poloxamer-188 is 100:(2-5). The invention provides the effective method which is capable of quickly dissolving dexibuprofen, the auxiliary usage is small, and the safety is high. Drug stability tests and animal safety tests indicate that the dexibuprofen product prepared by the method is safe and stable, and has a good drug effect. |