http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104138602-B
Outgoing Links
Predicate | Object |
---|---|
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
filingDate | 2014-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104138602-B |
titleOfInvention | Type II diabetes resisting long-acing nano complex peptides and preparation method and application |
abstract | Open a kind of type II diabetes resisting long-acing nano complex peptides of the present invention and preparation method and application.With nanometer selenium as carrier, chitosan is for connecting, it is achieved active polypeptide and the covalent bond of nanometer selenium particle.Nano combined peptide obtained by the present invention has in physiological environment and carries, protects and slow release therapeutical peptide, the effect of effective extended treatment polypeptide half-life; the effective dose playing therapeutical effect can substantially less than be used alone the dosage of therapeutical peptide, and can play the biological action of medicament slow release, long-acting treatment;Overcome when being used alone therapeutical peptide, owing to molecular weight is little, the shortcoming the most easily removed by tachymetabolism, Half-life in vivo and the bioavailability of small molecule therapy polypeptide can be effectively improved.The nano combined peptide of the present invention can be applicable to preparation treat following disease medicine: diabetes, hyperglycemia.The preparation method efficiency of the present invention is high, low cost, has a extensive future. |
priorityDate | 2014-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 221.