| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f47c750954e13a1ed0be96c1bf1c51c7 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-68 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-426 |
| filingDate |
2013-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66d817a5310e06f2ebfde861d1651bbb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54f4a588f5dc72ab13b273bf4e3ee504 |
| publicationDate |
2014-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-104136423-A |
| titleOfInvention |
Ribonucleotide reductase inhibitors and methods of use |
| abstract |
The present invention provides novel compounds that inhibit ribonucleotide reductase (RR) by binding to RRM2 and interfering with RRM1/RRM2 holoenzyme activity and methods for synthesizing these novel compounds. Said compounds can be used to inhibit RR activity and to treat various pathologies associated with RRM2 expression, like for example certain cancer types, mitochondrial diseases or degenerative diseases. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110475475-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108431224-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017036398-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108431224-A |
| priorityDate |
2012-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |