http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104130972-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-075 |
| filingDate | 2014-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104130972-B |
| titleOfInvention | Primordial follicle activator and applications thereof |
| abstract | The invention discloses a primordial follicle activator and applications thereof. The activator comprises an mTOR signal path activator I and II, wherein the mTOR signal path activator I is 50 to 200 [mu]M of phosphatidic acid, and the mTOR signal path activator II is 20 to 50 [mu]M of propranolol; and a PI3K signal path activator composed of a PI3K signal path activator III and IV; wherein the PI3K signal path activator III is 30 to 100 [mu]M of bpV, and the PI3K signal path activator IV is 250 to 500 [mu]g/mL of 740Y-P. The invention relates to an in-vitro activated kit, which co-uses mTOR and PI3K signal path activators to activate primordial follicle cells in ovarian tissues of mouse and human and promote the growth of ovarian follicle. The kit can be widely used to assist the treatment on diseases caused by deficient ovarian follicle storage such as premature ovarian failure in the fertility field. |
| priorityDate | 2014-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 74.