http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104130313-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 |
| filingDate | 2014-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104130313-B |
| titleOfInvention | Synthetic bursin BPP-II specific binding peptides and application thereof |
| abstract | The invention discloses a kind of Synthetic bursin BPP II specific binding peptides and application thereof, belong to protein and peptide technical field.The aminoacid sequence of Synthetic bursin BPP II specific binding peptides is: small peptide 1:QSLPSPLWIQQS, small peptide 2:DRMPDSAWTTRK, small peptide 3:ALWPPNLHAWVP.The present invention is using BPP II BSA fusion protein as target molecule, by phage random 12 peptide library selection, identify in conjunction with ELISA and Competitive assays is tested, it is thus achieved that the phage specific binding with BPP II, carry out sequencing, synthetic BPP II specific binding peptides.Thus screen the combination Toplink obtained specific binding with Synthetic bursin BPP II, and suppress BPP II to mice WEHI 231B proliferation of lymphoma cells under finite concentration, having a good application prospect in terms of the medicine of preparation suppression Synthetic bursin BPP II anti-tumour cell proliferative, research and development and application for BPP II inhibitor lay the foundation. |
| priorityDate | 2014-05-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 129.