http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104130273-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-36
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04
filingDate 2014-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2016-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104130273-B
titleOfInvention A kind of synthetic method of ceftriaxone sodium
abstract The invention discloses the synthetic method of a kind of ceftriaxone sodium, it is first mixed solvent with dimethyl carbonate and organic acid, boron trifluoride methylcarbonate is that 7 ACA are generated 7 ACT with triazine ring condensation by catalyst, make 7 ACT and MEAM react generation ceftriaxone by tetramethyl guanidine as cosolvent again, be eventually adding sodium acetate and become sodium salt.This invention operational approach is simple, mild condition, and raw material is easy to get, pollute little, cost is the lowest, and the Qusong sodium product purity finally given is more than 99.6%, and molar yield is more than 94%.
priorityDate 2014-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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