http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104130248-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 |
| filingDate | 2014-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104130248-B |
| titleOfInvention | The preparation method of razaxaban |
| abstract | The invention belongs to technical field of medicine synthesis, it relates to the preparation method of a kind of anticoagulation medicine, particularly relate to the preparation method of a kind of FXa inhibitor razaxaban. The method comprises makes formula (VI) compound and formula (II) compound or formula (III) compound react in the presence of an organic base, obtain finally obtaining the step of formula X compound and razaxaban with following formula (VII) compound intermediate. The present invention has the advantage of at least one aspect following: synthesis step is short, receipts rate height, avoid using severe toxicity and/or expensive reagent, be applicable to suitability for industrialized production, impurity such as R content of isomer is low. |
| priorityDate | 2014-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 133.