http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104127881-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 |
| filingDate | 2014-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104127881-B |
| titleOfInvention | Fatty acid mating type albumin-medicament nano particle lyophilized preparation and preparation method |
| abstract | The invention discloses a kind of fatty acid mating type albumin-medicament nano particle lyophilized preparation and preparation methods, utilize the high-affinity and its stable bond characteristic between fatty acid and albumin specific position, it is made under the action of high shear force using fatty acid as the nanoparticle of core, and make " water-insoluble " or " water solubility " drug in the form of " solution " or " super micro nano particle ", one or more " package " or " in conjunction with " wherein, and obtain various nanoparticle suspension, through removing organic solvent, degerming, it is dry, obtain lyophilized preparation.Product of the present invention is only made of albumin, drug and fatty acid, without any auxiliary material, it is high with nanoparticle integrality in solution in vitro and in blood circulation inside body and stability, dramatically increase the LD that load drug is significantly improved rich in the medicament contg in gp60 recipient cell or in tumor tissues 50 And MTD, close the biological properties such as the antigen site of institute " package " or " in conjunction with " albumen. |
| priorityDate | 2014-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 215.