http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104119361-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-36 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-36 |
| filingDate | 2014-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104119361-B |
| titleOfInvention | A kind of process for purification of new antibiotic compound |
| abstract | The present invention relates to a kind of process for purification of new antibiotic compound, preparation process is as follows: (1) salify: cefazedone and Sodium isooctanoate solvent are placed in anhydrous methanol, carry out salt-forming reaction, treat that cefazedone dissolves completely, control temperature is at 15-35 DEG C; (2) decolour: gac is added in reaction solution, stir decolouring, then cross filtering gac, keep filtrate temperature to be 10-30 DEG C, and then filter; (3) crystallization: first add a certain amount of acetoneand ethyl acetate in the filtrate after filtration, control temperature 15-20 DEG C, growing the grain 1-2 hour, and then add a certain amount of acetoneand ethyl acetate, keep stirring velocity 80-120 rev/min of stirring and crystallizing, control temperature is at 15-25 DEG C, then growing the grain 2-4 hour; (4) dry: filtration, washing leaching cake, dry, obtain cefazedone sodium fine work.This preparation method compared with prior art compare simple to operate, cost is low, yield is high, pollute greatly reduce; Gained cefazedone sodium fine work moisture content is low, foreign matter content is low, stability is high. |
| priorityDate | 2014-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.