Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_658df3b9d24eb5224b37aaf605741db6 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-31 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-27 |
filingDate |
2012-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcbaf0d8ff1a66ae5d8442e841847a70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e01b7888274f0b3c3d03e26e8415a164 |
publicationDate |
2014-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-104114183-A |
titleOfInvention |
CTP-based insulin analogs for the treatment of diabetes |
abstract |
Insulin analogues comprising non-native glycosylation site sequences having high potency and specificity for the insulin receptor are provided. In one embodiment, a peptide sequence greater than 18 amino acids is used as a linking moiety linking human insulin A and B chains or analogs or derivatives thereof to provide a high potency single chain insulin analog. In one embodiment, the linking moiety comprises one or more glycosylation sites. Prodrug and conjugate derivatives of the insulin analogs are also disclosed. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11471513-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018032786-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11472863-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2568624-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018032785-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2568624-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018032787-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018032637-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105061566-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11123438-B2 |
priorityDate |
2011-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |