http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104109254-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L29-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J5-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L89-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L5-04 |
filingDate | 2014-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104109254-B |
titleOfInvention | I-type collagen-sodium alginate-polyvinyl alcohol composite film and preparation method thereof |
abstract | The invention provides an I-type collagen-sodium alginate-polyvinyl alcohol composite film which comprises the following components by weight percent: 20% to 60% of I-type collagen, 20% to 60% of sodium alginate and 20% to 60% of polyvinyl alcohol. A preparation method of the composite film comprises the following steps: firstly, respectively dissolving the I-type collagen, the sodium alginate and the polyvinyl alcohol in different reaction kettles and regulating the pH of the I-type collagen to be within 5 to 8; then, successively adding a sodium alginate liquid and a polyvinyl alcohol liquid in proportion into an I-type collagen liquid and stirring for 4 to 10 hours; adding a defoaming agent to a mixed liquid and stirring for 20 to 60 minutes; then, pumping the mixed liquid into a storage tank and standing for defoaming; after the defoaming is checked to reach a requirement, pumping the mixed liquid into a film casting machine so as to obtain a film in a casting manner, drying and soaking the film in a cross-linking agent liquid or standing under a cross-linking condition for cross-linking for 4 to 24 hours, cleaning and drying; finally, shaping the film, packaging and irradiating, thereby obtaining the I-type collagen-sodium alginate-polyvinyl alcohol composite film. The composite film material is good in mechanical property, hydrophilcity and biocompatibility, moderate in degradation velocity and simple in preparation process. Thus, the composite film material can be widely applied to wound dressing, hemostatic materials, tissue engineering scaffold materials and the like. |
priorityDate | 2014-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.