http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104109104-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3cce30a5cea77a562682658ca3617c1a |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C241-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C243-22 |
| filingDate | 2014-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3060d9fa124ac4d3e4672c979048904 |
| publicationDate | 2014-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104109104-A |
| titleOfInvention | Preparation method of 3-chlorophenylhydrazine hydrochloride |
| abstract | The invention relates to a preparation method of 3-chlorophenylhydrazine hydrochloride, which comprises the steps of diazotization, reduction, purification and salification. In the diazotization and reduction steps, concentrated hydrochloric acid is utilized to keep the reaction solution strongly acidic, thereby ensuring the smoothness and completeness of the reaction. In the reduction step, zinc powder-concentrated hydrochloric acid, which is used as a reducer instead of sodium thiosulfate, sodium bisulfite, stannous chloride-hydrochloric acid or the like, has the advantages of favorable reducibility, high yield and shorter reaction time, and zinc hydroxide and other impurities generated by the reaction can be removed conveniently, so that the product has fewer impurities and high purity; and in the salification step, acetone is used for eluting, thereby enhancing the purity of the product and ensuring the appearance of the product. The preparation method has the advantages of stable and reliable technique, high product purity (the content is greater than or equal to 99% by high performance liquid chromatography) and high yield (greater than or equal to 39%), is easy to operate, and completely satisfies the market demands for 3-chlorophenylhydrazine hydrochloride. |
| priorityDate | 2014-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.