http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104098548-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 |
| filingDate | 2013-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104098548-B |
| titleOfInvention | A kind of refining method of Delafloxacin |
| abstract | The invention relates to the technical field of purification methods of delafloxacin. The method for refining delafloxacin of the present invention includes adding delafloxacin into a polar aprotic solvent, heating, stirring until dissolved, adding distilled water, gradually cooling down and crystallizing to obtain high-purity delafloxacin. The delafloxacin prepared by the existing synthetic method needs to be further refined, and the preparation by simple column chromatography will inevitably increase the difficulty of large-scale production, and will greatly increase the preparation cost. The present invention can effectively remove impurities, so that the compound 1 delafloxacin can reach Higher purity (>99.0%), and meet the needs of subsequent preparations. |
| priorityDate | 2013-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.