http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104086450-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C55-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-138 |
filingDate | 2014-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104086450-B |
titleOfInvention | Crystal formation δ of succsinic acid S-metoprolol and its preparation method and application |
abstract | The invention discloses the crystal formation δ of succsinic acid S-metoprolol, described crystal formation comprises the characteristic peak that following 2 θ reflection angle measure in X-ray powder diffraction: 3.98 ± 0.1,7.95 ± 0.1,10.92 ± 0.1,12.28 ± 0.1,14.66 ± 0.1,16.02 ± 0.1,18.39 ± 0.1,19.77 ± 0.1 and 20.99 ± 0.1.This stability of crystal form is good, and dissolution rate is slow.Present invention also offers preparation method and the application thereof of this crystal formation, it is high that the crystal formation δ using the method to prepare succsinic acid S-metoprolol has repeatability, the feature of strong operability, can be used for pharmaceutical compositions, in the hypertensive medicine of preparation treatment, have important application value. |
priorityDate | 2014-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.