http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104072678-B

Outgoing Links

Predicate Object
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F222-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-08
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-58
filingDate 2013-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2017-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104072678-B
titleOfInvention Polymer microsphere, preparation and applications thereof
abstract The invention relates to a mono-dispersed core-shell structure polymer nano particle, preparation and applications thereof. At first, monoene functional monomers and polyene crosslinking monomers are polymerized to generate polymer particles taken as the cores of the polymer microsphere, and then 3-acrylamino phenylboronic acid (APBA) and polyene crosslinking monomers are covered on the surface of the cores through a reversible addition-fragmentation chain transfer (RAFT) polymerization technology so as to obtain smooth core-shell polymer nano particles containing boronic acid functional groups. Phenylboronic acid functional groups are introduced to the material surface through a RAFT method, thus the defects existing in the conventional post modification method such as tedious steps, low reaction efficiency, and unstable morphology of direct polymerized products are avoided, moreover, the APBA can be more stably polymerized, and the bonding amount of boronic acid on the surface is increased at the same time. The polymer nano particle can be used to separate or enrich glycoprotein in a 1,2-cis-diol structure, and has a very good practical value and application prospect in fields like proteomics, etc.
priorityDate 2013-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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