http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104072618-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
filingDate | 2014-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104072618-B |
titleOfInvention | Artificial constructed hybrid ubiquitin integrated structure domain polypeptide and its application |
abstract | The invention discloses a kind of artificial constructed hybrid ubiquitin integrated structure domain polypeptide and its application.Hybrid ubiquitin integrated structure domain polypeptide provided by the present invention, is in series by least two ubiquitin binding structural domains;And in all ubiquitin binding structural domains for forming the hybrid ubiquitin integrated structure domain polypeptide, at least two ubiquitin binding structural domains are different.In addition, the hybrid ubiquitin integrated structure domain polypeptide can also contain label protein.Experiment proves, hybrid ubiquitin integrated structure domain polypeptide provided by the invention can efficiently, the different ubiquitin chains of the combination ubiquitin molecule of unbiasedness and its carrying, the bioaccumulation efficiency of extensive ubiquitin protein matter can be improved, for developing efficient ubiquitin protein matter separating medium and biochemical reagents, or the adjusting of vivo protein ubiquitination provides technological means.The present invention is for promoting the research of human diseases sample ubiquitin protein matter group and the development of healthy medicine to be of great significance. |
priorityDate | 2014-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 254.