http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104069109-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06 |
| filingDate | 2014-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104069109-B |
| titleOfInvention | Application of substituted piperazine-1,4-diamide compounds in pharmacy |
| abstract | The invention relates to an application of substituted piperazine-1,4-diamide compounds in pharmacy. The substituted piperazine-1,4-diamide compounds can be used as an activating agent of SIRT1 (Silent Information Regulator 1) for activating nuclear receptors LXRalpha and LXRbeta, regulating expression of target proteins ABCA1/G1, inflammatory key proteins p65, senescence-associated genes p662hc and the like, promoting excretion of lipid and cholesterol, regulating cholesterol metabolism, inflammation-associated and senescence-associated genes or proteins, treating cardiovascular and cerebrovascular diseases, regulating blood lipids and resisting atherosclerosis, inflammatory reaction and senescence diseases. |
| priorityDate | 2014-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 86.