http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104059204-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7d71f3f8888b7105262efff49755f58f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F220-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F292-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F212-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F8-44 |
| filingDate | 2014-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d58d105e5774ccb5304de7a747ac4e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f0c7c883904d1edab0639f5b899cab09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_266952812167904a544ae70f78344147 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea4850e17647db0c65dc3bca0008027b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ab1eea7b18025c35b94074db86ab780 |
| publicationDate | 2014-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104059204-A |
| titleOfInvention | Surface cation magnetic polymer microsphere, and preparation method and application thereof |
| abstract | The invention discloses a surface cation magnetic polymer microsphere which is prepared through the following steps: embedding magnetic metal oxide nanoparticles in a micron-sized crosslinking polystyrene microsphere, thus obtaining a monodisperse micron-sized magnetic polymer microsphere; and in the presence of initiator and surfactant, copolymerizing an amino functional monomer vinylbenzyl trimethyl ammonium chloride and styrene on the surface of the micron-sized magnetic polymer microsphere, wherein by regulating the ratio of the styrene to the vinylbenzyl trimethyl ammonium chloride, the obtained microsphere can be efficiently combined with 50-1000bp small-fragment DNA, can be used as a plasma free small-fragment DNA extraction reagent and can be further prepared into a plasma free small-fragment DNA extraction kit. By optimizing other reagent components in the kit, a small amount of free small-fragment DNA can be efficiently extracted and separated from plasma, the extraction yield is high, the repetitiveness is good, the operation is convenient, and the cost is low. The microsphere can be used for an automatic operating platform, thereby being beneficial to large-scale popularization and application. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104513819-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110106170-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109001464-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111206440-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111871381-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111077304-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110106170-B |
| priorityDate | 2014-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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