http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104045639-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-18 |
| filingDate | 2014-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104045639-B |
| titleOfInvention | A kind of preparation method of figured silk fabrics acyclovir |
| abstract | The present invention relates to chemical field, particularly relate to the preparation method of figured silk fabrics acyclovir, step is: A, at N, add acyclovir and CBZ-L-α-amino-isovaleric acid in dinethylformamide solution, control temperature 20-30 DEG C, adds reaction additives, reaction times 10-15 hour, obtains X2 and X3 reaction solution; B, in reaction solution, add carbon dust, be cooled to 0 ± 2 DEG C of mistake and filter X3 material, the filtrate containing X2 is concentrated, crystallization purifying obtains X2; C, the X2 of step B gained is dried after, dissolved in by X2 in organic solvent, add palladium-carbon catalyst, pass into hydrogen, at 20-25 DEG C, react 5-10 hour, reaction terminates to filter, and after filtrate is concentrated, crystallization purifying obtains X1 target product.The method is simple to operate, clean environment firendly, yield are high, equipment investment is few. |
| priorityDate | 2014-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.