http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104042570-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e95825c04f3c7c83e774c4bd8b80c9cd |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 |
| filingDate | 2013-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f288eb5d1db81c5178030681bb08c292 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c66d3ee3c414a7493996f2baef916f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9548c7f141f66be2f7468a176d04c2df http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4776fe835bc8ef8c1a4697b76ae700e6 |
| publicationDate | 2014-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104042570-A |
| titleOfInvention | Preparation method for venlafaxine hydrochloride sustained-release pellet |
| abstract | The invention discloses a preparation method for a venlafaxine hydrochloride sustained-release pellet. The method comprises the steps of: subjecting MCC to centrifugal granulation, adjusting the guniting speed and powder feeding speed till the material flows in a flocculent state and maintains the flocculent flow state, feeding powder and controlling the powder-slurry ratio to prepare a microcrystalline cellulose blank pellet core; crushing bulk drug powder, mixing the powder with MCC and HPMC (3cp) evenly in proportion, employing a powder lamination technique, taking the MCC blank pellet core as a mother nucleus and adopting water as a wetting agent, adjusting the guniting speed and powder feeding speed, the rotational speed of a main engine, air jetting flow, air jetting pressure and air blast, at the end of powder feeding, polishing the pellet in a pot for 5min, and conducting drying for 24h in a 40DEG C drying oven after removal from the pot so as to obtain a venlafaxine hydrochloride pellet; conducting coating on the venlafaxine hydrochloride pellet, making Surelease, HPMC and TEC into a Surelease coating solution in proportion, and making Sureleae NG and TEC into a Surelease NG coating solution according to a proportion. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106176679-A |
| priorityDate | 2013-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.