http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104031286-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76b58061e0905cbafeea07a17dfecb22 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56 |
filingDate | 2014-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1af9484d579fd94378563543715154b1 |
publicationDate | 2014-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104031286-A |
titleOfInvention | Preparation method of porous heparin nanospheres |
abstract | The invention relates to the technical field of processing biopolymer materials and in particular relates to a preparation method of porous heparin nanospheres. The preparation method comprises the following steps: firstly preparing a heparin solution, performing electrostatic sphere jetting by use of non-spinnability of the heparin and by use of an electrostatic spinning device, quickly freezing the jetted nanospheres by use of liquid nitrogen so that the molecular chain of the heparin can be quickly fixed in the nanospheres, and then carrying out a freeze-drying process to obtain the porous heparin nanospheres having a spatial reticular structure. The preparation method of porous heparin nanospheres is simple, the prepared porous heparin nanospheres have a relatively large specific surface area and are capable of achieving relatively high anticoagulation effect in short time, and meanwhile, the crosslinked porous heparin nanospheres have certain strength and water resistance, and thus has potential application value in aspects such as drug release and slow release, and tissue engineering scaffold materials. |
priorityDate | 2014-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.