http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104031014-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K2211-1088 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
| filingDate | 2013-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104031014-B |
| titleOfInvention | Coumarin derivative and preparation method thereof and elastase activity detection method and detection kit |
| abstract | The invention provides a kind of coumarin derivative, this coumarin derivative as the formula (1), wherein, R 1 For the one in pentafluoroethyl group and seven fluoropropyls, R 2 For the one in trifluoromethyl, methyl, cyano group, pyridine ring and benzothiazole ring; The present invention also provides the application of coumarin derivative in the activity that detects elastoser, and a kind of detection method of elastoser, and a kind of active detection kit of elastoser. Coumarin derivative fluorescence probe provided by the invention when detecting relevant application with elastase activity highly sensitive, high with the affinity of enzyme, atom utilization is high, and coumarin derivative of the present invention is the fluorescence probe of non-peptide class, higher than peptide class fluorescence probe stability, use more convenient, price is cheaper. Formula (1). |
| priorityDate | 2013-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 134.