abstract |
The present invention relates to a kind of method of synthesizing carbazole compound, is in 1,3-bis(2,6-diisopropylphenylimidazol-2-ylidene) gold (I) acid chloride/silver hexafluoroantimonate Under catalysis, 1-(indol-2-yl)-2-yn-1-ol reacts with high regioselectivity to synthesize functionalized carbazole. The invention has the advantages of simple operation, easy access to raw materials and reagents, mild conditions, and reaction It has the advantages of high regioselectivity, multiple substituents can be introduced at the same time, the product is easy to separate and purify, and is suitable for the synthesis of various substituted carbazole compounds. |