http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104028181-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/H01F1-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J13-02 |
| filingDate | 2014-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104028181-B |
| titleOfInvention | There is noble metal/paramagnetic metal composite nanoparticle and the application thereof of nucleocapsid structure |
| abstract | The invention discloses a kind of noble metal/paramagnetic metal composite nanoparticle and the application thereof with nucleocapsid structure, the preparation method of described noble metal/paramagnetic metal composite nanoparticle comprises: (a) prepares the noble metal nano particles that particle diameter is 5-50nm; Described noble metal is gold or silver-colored; B () gets containing sulfydryl and amino compd A, noble metal nano particles and compd A are reacted, obtains product a; Make product a and methyl acrylate react again, obtain product b; C () gets containing azido group and amino Compound C, the product of step (b) and Compound C are reacted, obtains the noble metal nano particles of finishing azido group; D () is got the obtained product of step (c) and is carried out Click reaction with the smaller ligand containing alkynyl, obtain product d; E the chloride of product d and paramagnetic metal reacts by (), obtain described composite nanoparticle.Described noble metal/paramagnetic metal composite nanoparticle, can be used as MRI and CT and strengthens contrast medium. |
| priorityDate | 2014-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.