http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104024306-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G73-0233 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-065 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L79-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D265-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L79-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G73-02 |
filingDate | 2012-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104024306-B |
titleOfInvention | The conjugate and its medical application of polyoxazoline polymer and preparation method thereof, these polymer |
abstract | The present invention relates to poly- (2 oxazoline) polymer of functionalization, its carrier and/or conveying medium (conjugate) for being highly suitable as example small treatment molecule of medicine and bio-pharmaceuticals.These polymer are characterised by that they contain by [N (R 1 )‑(CHR 2 ) m ] represent repeat unit, wherein R 1 It is R 3 ‑(CHR 4 ) n ‑CONH‑R 5 ;R 2 It is selected from H and optionally substituted C 1‑5 Alkyl;R 3 It is CH 2 CO, C (O) O, C (O) NH or C (S) NH;R 4 It is selected from H and optionally substituted C 1‑5 Alkyl;R 5 It is H;C 1‑5 Alkyl;Aryl;Or the part containing the functional group that can be used in combining;M is 2 or 3;And n is 15;Or n is 0 and R 3 It is CH 2 .The present invention is further directed to the conjugate with least one active part such as treatment part, targeting moiety and/or diagnosis of partial of these polyoxazoline polymer, and is related to application of these conjugates in disease or the therapeutic treatment of imbalance, preventative process or diagnosis. |
priorityDate | 2012-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 546.