http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104017088-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33a62710796e131599043055d399597f |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2014-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc3a2fa9a3bf6808b8e350e494db0c52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55bb5e20d030f9ca9150cd1529fab0ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f159eace905746fafa7977e6dc95e85c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1aa7e9dbe041953160d692ed3c493342 |
publicationDate | 2014-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104017088-A |
titleOfInvention | Difunctional modified ferritin heavy chain subunit nanoparticles as well as preparation method and application thereof |
abstract | The invention discloses difunctional modified ferritin heavy chain subunit nanoparticles as well as a preparation method and an application thereof. The N end or the C end of FTH1 of the difunctional modified ferritin heavy chain subunit nanoparticles is modified with enhanced green fluorescent protein. The ferritin heavy chain subunit nanoparticles are modified with the enhanced green fluorescent protein (EGFP), are subjected to denaturation and renaturation together with nanoparticles modified with EGF at the same time and are self-assembled in vitro; and formed hybrid protein nanoparticles can specifically target to tumor cells and keep fluorescence activity. According to the preparation method of the nanoparticles, novel method and reference are provided for realizing functionalized modification of biomacromolecular nanocarriers, a very good model is provided for tumor cell targeted therapy of subsequently selected drugs, and the application prospect is very good. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110327308-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022206451-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109486827-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114380901-A |
priorityDate | 2014-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 85.