http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104016954-B

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-04
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-04
filingDate 2014-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2016-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104016954-B
titleOfInvention The preparation of Nebivolol Intermediates and purification process
abstract The present invention relates to a kind of preparation and purification process of Nebivolol Intermediates, specifically, relate to one to prepare and the chloro-1-of the 2-(6-fluoro-3 of purifying formula (I), 4-dihydro-2H-1-chromene-2-base) ethyl ketone improves one's methods, and this compound is the key intermediate of synthesis nebivolol.The highly purified solid of this key intermediate is obtained by the application's method height yield (reaching more than 85%), high purity (more than 99%), easy and simple to handle, be suitable for suitability for industrialized production.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018024017-A1
priorityDate 2014-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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