| abstract |
The present invention provides the compound of formula (I), wherein A, R 1 , R 2 , R 3 I , V, X, and Z is defined in this article, described compound is potassium channel inhibitors.The pharmaceutical composition of the compound that the present invention also provides for comprising formula (I) and purposes in the treatment thereof, especially in treatment by K ir 3.1 and/or K ir 3.4 or its any heteromultimers mediation or need suppress K ir 3.1 and/or K ir 3.4 or the disease of its any heteromultimers or disease in purposes. |