http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104004723-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-93 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y601-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N24-087 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N24-08 |
filingDate | 2013-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104004723-B |
titleOfInvention | 3,5-bis-fluoro tyrosine translation system and application thereof |
abstract | The present invention relates to a kind of aminoacyl tRNA synthetase mutant; it is a kind of orthogonal aminoacyl tRNA synzyme; the aminoacid sequence that it contains selects the group of the examples of conservative variations composition of the aminoacid sequence shown in free SEQ ID NO:4 and the aminoacid sequence shown in SEQ ID NO:4, and described examples of conservative variations has the enzymatic activity identical with the aminoacid sequence shown in SEQ ID NO:4.The present invention also provides for a kind of 3,5 two fluoro tyrosine translation system, and it comprises: (i) 3,5 two fluorotyrosine;(ii) the orthogonal aminoacyl tRNA synzyme of the present invention;(iii) orthogonal tRNA, wherein said orthogonal aminoacyl tRNA synzyme orthogonal tRNA described in described 3, the 5 two preferential aminoacylations of fluorotyrosine;(iv) nucleic acid of encoding target protein, wherein said nucleic acid contains at least one selection codon of described orthogonal tRNA specific recognition. |
priorityDate | 2013-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 170.