http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104004087-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-815 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-18 |
| filingDate | 2014-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104004087-B |
| titleOfInvention | A kind of Hirudo high F value oligopeptide and enzymolysis preparation thereof and application |
| abstract | The invention discloses a kind of Hirudo high F value oligopeptide and enzymolysis preparation thereof and application, preparation method includes: (1) Hirudo stem body tentatively cleans remove impurity, high speed pulverization；(2) raw material alkali pre-soaking；(3) alkaline protease Alcalase AF 2.4L combines papain double-enzyme hydrolysis；(4) activated carbon powder static adsorption removing aromatic amino acid is used；(5) the most isolated and purified with gel permeation chromatography post, collect and separate product, lyophilization, it is thus achieved that molecular weight is higher than the Hirudo oligopeptide powder of 20 less than 2000Da, F value (Fischer ratio, i.e. branched-chain amino acid and the ratio of aromatic amino acid molar content).Preparation process disclosed by the invention is simple, selects alkaline protease and two kinds of business enzymes of papain, it is easy to commercial production, and productivity is higher, has certain anticoagulant effect, and adds new source for high F value series products. |
| priorityDate | 2014-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.