http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104003939-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2014-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104003939-B |
| titleOfInvention | Diaryl substitution thiohydantoin class compound and preparation method and application |
| abstract | The invention discloses diaryl substitution thiohydantoin class compound, structure is as shown in logical formula (I)： Wherein, R 1 It is hydrogen, halogen or trifluoromethyl；R 2 It is hydrogen, halogen, trifluoromethyl, itrile group or alkoxy；R 3 It is hydrogen, halogen or itrile group；R 4 It is hydrogen or halogen；R 5 It is hydrogen, halogen, methyl, N methylcarbamoyls, N ethyls amine formyl, N isopropylamines formoxyl, N cyclopropylamine formoxyls.Diaryl substitution thiohydantoin class compound, especially 7b 7g of the invention, 7i 7k, 7m 7p, 7r 7t have stronger GIA, can be used for preparing antineoplastic to hormone-independent prostate cancer cell LNCaP. |
| priorityDate | 2014-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 155.