http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104001178-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 |
| filingDate | 2014-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104001178-B |
| titleOfInvention | A kind of PLGA nano-medicament carrier and its preparation method and application |
| abstract | The present invention provides a kind of PLGA nano-medicament carriers being made up of PLGA nanoparticles kernel and vanillic aldehyde cross-linked chitosan shell, and its preparation method is：Emulsifying agent is used as using PVA, dichloromethane and ethanol are scattered in aqueous phase for the PLGA organic phases of mixed solvent by an emulsion process and prepare PLGA microballoons, then chitosan solution is added, makes chitosan absorption in PLGA microsphere surfaces, adds the chitosan that vanillic aldehyde is crosslinked PLGA microsphere surfaces.This product has certain pH environment-responsives, and the control release of medicine can be realized according to internal pH environmental changes；Its stability is high, and the intake ability for the medicine that cell is contained to microballoon is strong；There is good application prospect in terms of the pharmaceutical carrier for treating tumour. |
| priorityDate | 2014-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.