http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104000824-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-423 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-433 |
| filingDate | 2014-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104000824-B |
| titleOfInvention | The application in preparing anti-HIV-1 virus drugs of the benzo five-membered heterocycle compound |
| abstract | The invention discloses the application in preparing anti-HIV-1 virus drugs of the benzo five-membered heterocycle compound, the formula of this compound is Or .Inventor utilizes the interaction of Vif-APOBEC3G, it was demonstrated that the benzo five-membered heterocycle compound of the compound of above-mentioned formula, the particularly present invention can suppress the activity of Vif protein degradation A3G, causes that the expression of screening system Green fluorescin will go up.It is further characterized by it by carrying out the infection experiment of wild type HIV-1 virus in the CD4+T lymphocyte series such as the primary CD4+T lymphocyte of people and H9, SupT1 there is good antivirus action.The strong theoretical basis provided for the research and development of further antiviral drugs and practical basis, have important research and development value and development significance. |
| priorityDate | 2014-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.