http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103992499-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J9-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-24 |
filingDate | 2014-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103992499-B |
titleOfInvention | A kind of 3D even porous timbering material and preparation method thereof |
abstract | The present invention relates to a kind of 3D even porous timbering material and preparation method thereof.Existing artificial bone supporting material porosity is little, limits cell migration and new organization and is formed, micropore size skewness, is unfavorable for the distribution at material surface such as osteoblast, and aperture is unfavorable for more greatly adhesion and the increment of cell.The present invention dissolves collagen protein in sodium carbonate liquor, adds nanometer hydroxyapatite, is sub-packed in mould freezing, vacuum drying, and successively cross-linking reaction under alkalescence and acid cross-linked environment, washs final vacuum lyophilization, sterilization packaging.The present invention is with collagen protein and nanometer hydroxyapatite as raw material, the formation pore-size distribution that distils of ice crystal is homogeneous and suitable cell adheres to, breeds and the aperture migrated and the microcellular structure of porosity to utilize sodium carbonate and acid reaction to generate in carbon dioxide and vacuum lyophilization, and the even porous support prepared i.e. has certain comprcssive strength and possesses again good microstructure and biocompatibility. |
priorityDate | 2014-04-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 49.