http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103992316-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac31afbea1cbbb03498644721ffb4a62 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2014-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d579a1ec47592b9b8bdd1917251858b9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8466e538cf3097a07150abc4d739b14a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d28dadb0cbc5da9c95a537eaa54393a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d341c8f721219271065d353b537781fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fa95c56a1b4c48832b2c205b8ceaf42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a19736c9cb662a358be212f31c263ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0be6b91089a442a86a9037081b9d206f |
| publicationDate | 2014-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103992316-A |
| titleOfInvention | A method for synthesizing 5-formonitrile-pyrrole [1,2-a] quinoline derivatives |
| abstract | The invention relates to a method for synthesizing 5-carbonitrile-pyrrole [1,2-a] quinoline derivatives, belonging to the technical field of chemical preparation. Using 2-haloaryl acetonitrile and 2-formyl azole compounds as raw materials, according to the material ratio of 1 to 1.5:1, take 2-formyl azole compound and 2-haloaryl acetonitrile dissolved in organic solvent, add alkali Under the protection of inert gas, stir at 100-130°C for 18-24 hours to obtain 5-carbonitrile-pyrrole[1,2-a]quinoline derivatives, and obtain pure products after cooling, extraction, drying and vacuum distillation. The beneficial effects of the present invention are as follows: (1) The reaction conditions are relatively mild, the catalytic activity is high, the reaction yield can reach 80%, the highest can reach 90%, and the product selectivity is high, and the substrate expansion range is wide. (2) The catalytic system avoids the participation of transition metals and strong bases, has low cost, is safe and convenient, and the reaction system has little environmental pollution. |
| priorityDate | 2014-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.