http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103980354-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-375 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 |
filingDate | 2014-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103980354-B |
titleOfInvention | Fungal immunomodulatory protein FIP-ppl and gene thereof |
abstract | The present invention uses genetic engineering means to provide a kind of new immune modulator FIP ppl deriving from fungus first.The present invention also provides for and has synthesized the gene of the above-mentioned albumen of coding, and described albumen FIP ppl has immunomodulating and antitumor action.Being verified by experiments, splenocyte is had by described albumen urges splitting action, and can increase the synthesis of cytokine 2;The present invention have also demonstrated described albumen and hepatocellular carcinoma H22 and stomach cancer cell MGC823 be respectively provided with obvious Inhibit proliferaton and apoptosis-induced effect.The albumen FIP ppl of the present invention is low with the most fungal immunomodulatory protein homologys having been found that, is a kind of novel immunomodulating and antineoplastic biologic preparation. |
priorityDate | 2014-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.