http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103980205-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 |
| filingDate | 2014-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103980205-B |
| titleOfInvention | N-3-substituted sulfonamides ethyl-5-cyclopropane toroid hydantoin derivatives and its preparation method and application |
| abstract | The present invention relates to the novel cyclopropane toroid hydantoin derivatives containing sulfonamide substitutions base, its structural formula is:n r in formulan 1 for phenyl and the heterocyclic arene base of phenyl, replacement.Its method for making is: after 1-carboxyl-2,2-dimethyl cyclopropane carboxylic acid's ethyl ester and Vinyl chloroformate being reacted, at NaNn 3 effect is lower generates 1-acid azide-2,2-dimethyl cyclopropane carboxylic acid ethyl ester; 1-acid azide-2; 2-dimethyl cyclopropane carboxylic acid ethyl ester is reset through Curtius and is generated corresponding isocyanic ester <b>; </b> isocyanic ester and reacting ethylenediamine obtain N-3-(2-is amino) ethyl-5-cyclopropane toroid hydantoin, then react with corresponding SULPHURYL CHLORIDE in the basic conditions and generate target cyclopropane toroid hydantoin derivatives.The compounds of this invention has goodish anti-convulsant activity, and preparation method is simple, productive rate is higher. |
| priorityDate | 2014-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 73.