http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103976976-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 |
| filingDate | 2014-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103976976-B |
| titleOfInvention | A kind of bag carries the method for making of human growth hormone recombinant's small capsule of slow-soluble medicine |
| abstract | A kind of bag of the present invention carries the method for making of human growth hormone recombinant's small capsule of slow-soluble medicine, and with good biocompatibility, degradable multi-arm polyethylene glycol-PLA block polymer material is carrier material, and raw material is easy to get. Multiarm polymers has less hydrodynamic volume and lower viscosity, and its degradation rate is larger than linear polymer, is more conducive to load and the conveying of medicine. The carrying medicament ability that multi-arm polyethylene glycol-polylactic-acid block copolymer has had is amphipathic with uniqueness, can prevent the absorption of protein and hides the identification of reticuloendothelial system and engulf, and easily passes through physiologic barrier. Method for making of the present invention is simple, does not need complicated emulsion forming process; The good stability of micro-capsule, has improved human growth hormone recombinant's bioavilability, and human growth hormone recombinant's content is up to 46-81%. The envelop rate that bag carries human growth hormone recombinant's small capsule of slow-soluble medicine reaches 91%, good stability, and uniform particle diameter, reproducible, be applicable to large-scale production. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9878039-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10328535-B2 |
| priorityDate | 2014-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 120.