http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103976958-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 |
filingDate | 2014-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103976958-B |
titleOfInvention | Application of gold nanoparticles in preparing anticoagulants or antiplatelet drugs |
abstract | The invention discloses application of substituted pyrimidine molecule modified gold nanoparticles in preparing anticoagulants or antiplatelet drugs. The substituted pyrimidine molecule for modifying the gold nanoparticles is one or a mixture of at least two of 2-thiol-4,6-diaminopyrimidine, 2-thiol-4-aminopyrimidine and 2-thiol-4,6-dihydroxylpyrimidine. According to the gold nanoparticles, the substituted pyrimidine part without anticoagulant activity is connected with gold nanoparticles without anticoagulant activity through an S-Au bond to be applied to the anticoagulation field for the first time; the substituted pyrimidine molecule modified gold nanoparticles obtain unexpected anticoagulation effect, the preparation method is simple, the nanoparticles are small in diameter distribution and can be well dispersed in water, cannot cause bleeding side effect in normal dosage, and can be used for preparing anticoagulants or antiplatelet drugs. |
priorityDate | 2014-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.