http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103974716-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4846 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6815 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-04 |
filingDate | 2012-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103974716-B |
titleOfInvention | Factor VII and VII a derivative, the conjugate including it and complex and application thereof |
abstract | nullThe present invention relates to factor VII derivative,Novoseven derivative,Each by the polymer that can extend blood halflife being connected to Fac VII and Fac VII a conjugate prepared by this derivative,Each by carrier being connected to Fac VII and VII a complex prepared by this conjugate,The gene of coding Fac VII and Fac VII a derivative,Expression vector including this gene,Introduce the transformant of this expression vector,Use the method that this transformant prepares Fac VII and Fac VII a derivative,Prepare Fac VII a conjugate and the method for complex,The Fac VII a complex prepared by the method,Including this derivative、Conjugate or complex as active component be used for prevent or treat haemophiliachemophiliac pharmaceutical compositions,And include this derivative、Conjugate or complex are as the pharmaceutical compositions for blood clotting of active component.Further, the present invention relates to prevention or treatment hemophilia or the method promoting blood clotting, it includes the said composition to subject.The Fac VII or Fac VII a derivative of the present invention can retain the active carrier of Fac VII or Fac VII a in conjunction with improving blood halflife simultaneously, and they can be widely used in and are developed for haemophiliachemophiliac effective prevention or treatment reagent. |
priorityDate | 2011-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 143.