http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103966161-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0775 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-074 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0735 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 |
filingDate | 2013-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103966161-B |
titleOfInvention | The stem cell cultivating system of microenvironment and purposes in a kind of analogue body |
abstract | The invention belongs to cell biology, relate to a kind of stem cell cultivating system intending internal microenvironment and purposes;The present invention utilizes agarose to build three-dimensional stent material, microenvironment dynamic cultivation stem cell in analogue body, makes stem cell maintain self, breed, go back to the nest and to endothelial cell directed differentiation.The present invention also compares two-dimentional cultivation and the three-dimensional stem cell biological function difference under normal and low-oxygen environment, utilize method and the imaging technique of EGFP gene spike, internal skin grafing and mending Apo E knock out mice endothelial injuries, from many aspects such as multipotency transcription factor expression, growth factor secretion, extracellular matrix components, cell membrane intracellular signaling molecule activation, measure three-dimensional stem cell and maintain self, breed, go back to the nest and to the Suiping of endothelial cell directed differentiation.The present invention can be used in injury of blood vessel reparation, and promote application based theoretical and the experimental basis of the early stage endothelialization again of injured blood vessel for stem cell therapy. |
priorityDate | 2013-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.