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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
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filingDate 2013-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103965302-B
titleOfInvention A kind of recombination super antigen SEB mutant, preparation method and application
abstract The invention discloses a kind of recombination super antigen Type B Staphylococcal enterotoxin mutant, also disclose preparation method and application.The present invention extracts the enterotoxin SEB genome for deriving from natural S. aureus, obtains postgenome for amino acid sites relevant to toxicity and carries out rite-directed mutagenesis, obtains Staphylococcus aureus enterotoxin mutant of the invention.The enhancing of SEB mutant activity and toxicity of the invention weakens, and can be used as anti-tumor immunotherapy medicaments or function of immune system adjusts drug, have preferable market prospects.
priorityDate 2013-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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