http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103961752-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L31-12 |
filingDate | 2013-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103961752-B |
titleOfInvention | Tissue regeneration guiding film and preparation method thereof |
abstract | The present invention relates to a kind of tissue regeneration guiding film and preparation method thereof, the method comprises: pre-treatment step, collects mammal peritoneum, for subsequent use after circulating water washing and depilation, preliminary defat; Remove antigen treatment step, adopt enzyme treatment process, alkali pretreatment, acid treatment process and high osmotic treatment technique to the further defat of peritoneum for subsequent use successively, remove immunogenicity; Collagen fiber shrink process step, dewaters successively to the peritoneum after going antigen process, removes non-hydrophilic material and washing process, the collagen fiber of peritoneum are shunk; Drying steps, peritoneum after shrink process is laid in culture dish surface, make the compacted zone contact culture dish of peritoneum, be transferred to rapidly pre-freeze 1-8 hour in-60 to-80 DEG C of refrigerators, then put into freeze dryer lyophilizing obtains bootable tissue regeneration collagem membrane after 24-36 hour.Guiding film of the present invention has compacted zone and weaker zone, and also have good biocompatibility, hydrophilic and self-bone grafting ability, degradation time in vivo is long. |
priorityDate | 2013-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 112.