http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103961369-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-585 |
| filingDate | 2014-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103961369-B |
| titleOfInvention | Herba Physalis pubescentis lactone P is preparing the application in antitumor drug |
| abstract | The invention discloses a kind of Herba Physalis pubescentis lactone P and prepare the application in antitumor drug, described Herba Physalis pubescentis lactone P is the compound of formula I structure, Late Cambrian Herba Physalis pubescentis lactone P of the present invention can by suppressing STAT3 kinases 705 tyrosine (Tyr705) phosphorylations, the expression of further downward tumor death resistant gene XIAP, Mcl-1, and then inhibition tumor cell propagation, inducing apoptosis of tumour cell Herba Physalis pubescentis lactone P obviously can suppress the growth of Several Kinds of Malignancy cell, comprises gastric cancer, pulmonary carcinoma, hepatocarcinoma, myeloma, breast carcinoma etc.Herba Physalis pubescentis lactone P, as the inhibitor of novel specific STAT3 signal path with anti-tumor activity, particularly when with resveratrol, arsenic trioxide coupling, shows excellent anti-tumor activity. |
| priorityDate | 2014-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 265.