http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103948938-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate | 2014-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103948938-B |
| titleOfInvention | Load the DNA self-assembled nano structures of thrombin, its preparation method and application |
| abstract | The invention discloses a kind of preparation method of the DNA self-assembled nano structures loading thrombin of standing, it comprises: utilize DNA paper folding technology, single strand dna is self-assembled into rectangular nanostructured; Thrombin is fixed on the surface of described rectangle nanostructured, and " lock " structure that an energy responds tumor vascular endothelium specific receptor is fixed on two long limits of described rectangle nanostructured, thus thrombin is closed wherein, and produce response in delivery to during neoplasm vascularity, thus realize thrombin to the targeted of neoplasm vascularity and controllable release; The DNA self-assembled nano structures of prepared loading thrombin can be used for intravenous injection, achieves the targeted therapy to tumor, has wide potential applicability in clinical practice. |
| priorityDate | 2014-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.