http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103948934-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2014-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103948934-B |
| titleOfInvention | Drug nanoparticle preparation based on complexing coating and preparation method and application |
| abstract | The invention discloses a drug nanoparticle preparation based on complexing coating, a preparation method and an application. The preparation comprises a complex formed by a poorly-soluble drug, a polyphenol compound, and metal ions; Firstly, a suspension of the poorly-soluble drug particles is obtained by solvent exchange; then with the rapid complexation effect of the polyphenol compound and metal ions, a stable coating layer is formed on the drug particle surfaces, so as to obtain the stable poorly-soluble drug nanoparticle preparation. The invention also discloses a monodisperse nanoparticle preparation of the poorly-soluble drug obtained by the method, and an application thereof. The poorly-soluble drug nanoparticle preparation of the invention is controllable in particle size, uniform in distribution, high in drug loading ratio, and good in stability. |
| priorityDate | 2014-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 88.