http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103945849-A

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filingDate 2012-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77d5c58217c181eed0f7a3189fb3141f
publicationDate 2014-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103945849-A
titleOfInvention Combination Therapy for Cancer
abstract The present invention relates to a combination drug comprising: AZD5363 or a pharmaceutically acceptable salt thereof, and a drug selected from MDV-3100 (also known as enzalutamide (enzalutamide)), AZD3514, abiraterone (or its ester precursor Drug: at least one androgen receptor signaling modulator such as abiraterone acetate) and bicalutamide or a pharmaceutically acceptable salt thereof. Each of these combinations can be used in the treatment of cancer. The present invention also relates to pharmaceutical compositions comprising such combinations, and also to methods of treatment comprising combining AZD5363 or a pharmaceutically acceptable salt thereof with at least one androgen receptor signaling modulator as described above. The agents are administered simultaneously, sequentially or separately to a warm-blooded animal such as a human to treat cancer. The invention also relates to a kit comprising this combination.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108486041-A
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priorityDate 2011-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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