http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103937864-B
Outgoing Links
Predicate | Object |
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classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-69 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18 |
filingDate | 2014-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103937864-B |
titleOfInvention | A kind of active polypeptide be separated from anchovy |
abstract | The object of this invention is to provide a kind of active polypeptide be separated from anchovy fermented liquid, the anti-neural cell injury polypeptide molecular weight that the present invention obtains is 2,181Da; Being made up of 11 seed amino acids such as aspartic acid, Threonine, L-glutamic acid, glycine, L-Ala, Isoleucine, tyrosine, phenylalanine, Histidine, Methionin and arginine, is the activated polypeptide of a kind of novel tool.The present invention obtain polypeptide at glutaminate in neural cell injury model, active polypeptide of the present invention add the survival rate that can significantly improve PC12 neurocyte, when final concentration is 50 μ g/mL, cell survival rate compares with damage group and improves 26.4%, effectively alleviates the neural cell injury of glutaminate induction.In addition, the research of the celelular mechanism of its neurocyte protection effect is found, active polypeptide add the total antioxidant capacity significantly increased in born of the same parents, and have certain promotion to the increase of SOD vigor. |
priorityDate | 2014-04-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.